Does Social Stress Accelerate Aging Of Immune System?



Stress, including traumatic experiences, work pressure, everyday challenges, and prejudice, hastens immune system ageing. Additionally, it may raise a person's risk of developing cancer, cardiovascular disease, and infections like COVID-19. A recently USC research shows.


The research, which was released on Monday in the Proceedings of the National Academy of Sciences, may help explain gaps in age-related health, as well as the unequal toll of the Pandemic, and it may also indicate to potential areas for treatment.




Understanding differences in age-related health is crucial as the global population of older people increases. According to senior study author and postdoctoral researcher at the USC Leonard Davis School of Gerontology Eric Klopack, immune system changes brought on by ageing are a main factor in declining health.

The subjects' blood samples were then examined using flow cytometry. It is a lab process that counts and divides blood cells into different groups as they move one at a time in a constrained stream in front of a laser.


As expected, those with higher stress levels had immunological profiles that appeared to be older. with a lower proportion of illnesses white blood cells and a higher proportion of worn-out white blood cells. Even after accounting for education, smoking, drinking, BMI, race or ethnicity, and stressful life experiences, the relationship between stressful life events and less ready-to-respond, or naive, T cells was still significant.

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